GENO — Turn your raw DNA into a personalized health plan

GENO is a genetic health platform that turns raw DNA files from 23andMe, AncestryDNA and MyHeritage into personalized supplements, a tailored diet plan, blood-work analysis and a daily health plan. Your raw DNA is processed entirely in your browser and never uploaded to any server.

What GENO does

• Reads raw DNA files from 23andMe, AncestryDNA and MyHeritage in the browser
• Generates a per-gene risk profile across cardiovascular, metabolic, cognitive, methylation, detox, longevity and inflammation categories
• Produces a personalized supplement protocol with dose, form, timing and rationale
• Produces a personalized diet plan with macros and food recommendations
• Reads uploaded blood-work labs and interprets biomarkers in genetic context
• Generates a daily supplement checklist (PDF) and full PDF reports
• Builds a daily health plan combining DNA + symptoms + labs

How it works

1. Upload your raw DNA — drop your raw file from 23andMe, AncestryDNA or MyHeritage. Processing happens entirely in your browser.
2. Get instant insights — within seconds, see your genetic risk profile, health plan and supplement and diet recommendations.
3. Take action — download a daily supplement checklist, share PDF reports with your doctor, track progress over time.

The Personalized Health Plan — what it actually produces

The Personalized Health Plan is GENO's flagship Pro feature. It is not a generic wellness PDF — it is a personalized daily protocol generated specifically for your DNA, the symptoms you report, and (optionally) your blood-work labs.

What it actually contains

1. Genetic summary — a one-paragraph overview of your most clinically relevant variants and what they mean together (e.g. "MTHFR TT + slow COMT + APOE ε3/ε4").
2. Daily supplement schedule — exactly which supplements to take, at what dose, in what form (e.g. methylfolate 5-MTHF vs folic acid), and at which time of day (morning / midday / evening / bedtime). Includes rationale tied to the specific variant driving each recommendation.
3. Diet pattern & meal anchors — the dietary template that fits your genetics (Mediterranean, MIND, low-GI high-fiber, high-protein, etc.), specific foods to prioritize, foods to limit, and macro targets when relevant.
4. Lifestyle interventions — exercise volume and type, sleep targets, stress-management priority, environmental considerations (air quality if GSTM1 null, hearing protection if APOE4, etc.).
5. Blood-work interpretation — if you uploaded labs, every biomarker is interpreted in the context of your genotype (e.g. LDL targets adjusted for APOE, homocysteine targets adjusted for MTHFR).
6. Conversation starters for your doctor — concrete questions and tests to discuss at your next visit (e.g. "Ask about Lp(a)", "Request fasting insulin", "Discuss preconception 5-MTHF").
7. Daily checklist (PDF export) — a printable one-page version organised by time of day so you can actually follow it.

Sample output (anonymized excerpt)

DAILY HEALTH PLAN — Profile: Sarah, 38
Generated from: 612,407 SNPs analyzed
Top genetic context: MTHFR C677T (TT), COMT Met/Met, VDR FokI Tt, FTO AT

── MORNING (with breakfast) ──────────────────────
• L-methylfolate (5-MTHF) ........... 400 mcg
    why: MTHFR TT — ~65% reduced enzyme activity
• Methylcobalamin (B12) ............. 500 mcg
    why: pairs with methylfolate; recycle homocysteine
• Vitamin D3 + K2 (MK-7) ............ 4000 IU + 100 mcg
    why: VDR FokI variant — target 25(OH)D 50 ng/mL
• Magnesium glycinate ............... 200 mg
    why: cofactor for MTHFR + COMT; calming for Met/Met
• Breakfast anchor: 30g+ protein (eggs, Greek yogurt)
    why: FTO AT — protein blunts genetic appetite signal

── MIDDAY ────────────────────────────────────────
• L-theanine (with any caffeine) .... 200 mg
    why: slow COMT — smooths catecholamine response
• Cap caffeine: 1 cup before noon, none after 12:00

── EVENING (with dinner) ─────────────────────────
• Omega-3 (EPA/DHA) ................. 1000 mg
    why: anti-inflammatory; supports cognition
• Trimethylglycine (TMG) ............ 1000 mg
    why: alternative methyl donor — supports MTHFR

── DIET PATTERN ──────────────────────────────────
Mediterranean + high-protein anchor at every meal.
Prioritize: leafy greens, lentils, fatty fish, EVOO.
Limit: refined carbs, sweetened drinks, char-grilled meat.

── LIFESTYLE ─────────────────────────────────────
• Aerobic exercise: 180 min/week (FTO offset)
• Daily 10-min walk after main meals
• Sleep target: 7.5-9h (slow COMT recovery)
• 10-min meditation (Met/Met stress sensitivity)

── BLOOD WORK FLAGS (from your March labs) ───────
• Homocysteine 11.2 µmol/L → above target (<8)
    action: continue methylfolate + B12, retest in 12 wk
• 25(OH)D 28 ng/mL → below VDR-adjusted target
    action: maintain D3 4000 IU, retest in 8 wk

── DISCUSS WITH YOUR DOCTOR ──────────────────────
• Request Lp(a) (one-time test, lifelong indicator)
• Discuss preconception 5-MTHF if planning family
• Sleep study referral if snoring or daytime fatigue

The plan refreshes whenever you upload new labs, change reported symptoms, or GENO incorporates new evidence. Available on the Pro plan ($8.49/month).

Pricing

All plans use the same browser-only DNA processing — your raw file never leaves your device. Cancel anytime; account deletion removes all stored metadata.

Privacy

Most genetic services upload your raw DNA to their servers. GENO doesn't. Every analysis runs entirely in your browser. We can't sell, share or lose what we never receive. Only your account email and subscription metadata are stored.

Genes covered

MTHFR · APOE · COMT · VDR · FTO · CYP1A2 · TCF7L2 · GSTM1 — and many more variants relevant to nutrigenomics.

GENO is informational only — not medical advice. Consult a qualified healthcare professional for medical decisions.