Supplements directory — Forms, doses and timing that take MTHFR, COMT and VDR into account

Forms, doses and timing that take MTHFR, COMT and VDR into account — including when to choose folinic acid over methylfolate and hydroxocobalamin over methyl-B12.

Catalog (4)

• L-Methylfolate — L-Methylfolate (5-MTHF) — The bioactive form of folate the body actually uses. Often recommended for MTHFR variants, but not always the best fit when COMT is slow.
• Hydroxo-B12 — Hydroxocobalamin (B12) — A non-methylated form of vitamin B12 that's well tolerated by people who get jittery, anxious or wired from methylcobalamin.
• Vitamin D3 — Vitamin D3 (Cholecalciferol) — The form of vitamin D the body makes from sunlight. The right dose depends on your baseline, body weight, latitude — and your VDR genotype.
• Magnesium Glycinate — Magnesium Glycinate — A well-absorbed, gentle form of magnesium that supports sleep, muscle relaxation, blood sugar control and over 300 enzymatic reactions.

Informational only — not medical advice. Discuss treatment changes with a qualified healthcare professional.